22.04.2026
Patients with coronary artery disease (CAD) and type 2 diabetes mellitus (T2DM) experience significant changes in the cardiovascular system. These changes are associated with atherosclerotic damage to the coronary arteries and metabolic disturbances characteristic of diabetes. Functional studies aimed at identifying latent ischemic episodes, cardiac arrhythmias, and assessing exercise tolerance are important in a comprehensive assessment of these patients.
Holter ECG monitoring (24-48 hours) allows for the detection of silent ischemic episodes of the heart muscle, the frequency and nature of arrhythmias, and the assessment of heart rate variability. In patients with T2DM, this parameter is often reduced due to diabetic autonomic neuropathy.
24-hour blood pressure monitoring (ABPM) helps determine a 24-hour blood pressure profile, identify the "non-dipper" phenomenon characteristic of diabetes (lack of pressure drop at night), and evaluate the effectiveness of antihypertensive therapy. Echocardiography (EchoCG) is used to assess structural and functional changes in the heart muscle: left ventricular hypertrophy, diastolic dysfunction, areas of hypokinesia, and ejection fraction are detected. These data are important for determining the degree of heart failure and treatment strategy.
Treadmill testing (or bicycle ergometry) is used to determine exercise tolerance and detect exercise-induced ischemia. This test should be performed with caution in patients with type 2 coronary artery disease, as they have a high risk of latent ischemic changes and vascular complications.
This set of methods allows for a comprehensive assessment of the cardiovascular system in patients with coronary artery disease and type 2 coronary artery disease, the identification of early signs of the disease, and the adjustment of therapy aimed at reducing the risk of complications.